Salmonella: From Genome to Function-9781904455738

Description

Salmonella remains one of the world’s most consequential bacterial pathogens, causing an estimated one million deaths and around 100 million human infections each year. Its genetic landscape is shaped by frequent lateral gene transfer layered on a stable core genome, producing extraordinary diversity in host range and disease traits. That diversity—alongside growing genomic data—puts Salmonella research at a particularly dynamic moment.

Salmonella: From Genome to Function gathers expert reviews that survey the latest insights into how genome content, structure, and regulation translate into survival strategies, pathogenic potential, and ecological niches. Edited by Steffen Porwollik, the volume covers modern approaches to sub‑species classification and phage typing, comparative genomics, and identification of genetic determinants that allow Salmonella to thrive in each environment it encounters.

Key areas include molecular characterizations of small RNAs, fimbriae, flagella, and secreted virulence factors; host‑pathogen interactions focused on S. Typhi pathogenesis and immune response; biofilm formation; and the eye‑opening prospect of using Salmonella as an anti‑tumor delivery agent due to its unusual affinity for tumors. Together, these themes provide a timely snapshot of a field where genomic data fuels new hypotheses and applications. This is essential reading for researchers working on Salmonella or related bacteria, and recommended for broader bacterial genomics, molecular biology, and pathogenesis libraries.

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