Epigenetics: A Reference Manual (Hardback) — Craig & Wong (Eds.)

Description

Epigenetics explores how gene activity is regulated without altering the underlying DNA sequence, revealing mechanisms that shape development, health, disease, and inheritance across generations. As this field has rapidly expanded, epigenetic research has become central to modern biology, medicine, and genomics.

Epigenetics: A Reference Manual brings together leading international scientists to deliver an authoritative and wide-ranging overview of contemporary epigenetic research. Across 26 in-depth chapters, the volume examines core molecular mechanisms such as DNA methylation, histone modification, chromatin organization, non-coding RNA regulation, and epigenetic memory, alongside emerging technologies that enable genome-wide analysis and precise epigenomic profiling.

The book addresses epigenetic regulation across diverse biological systems, including plants, mammals, and human disease models, with particular attention to cancer epigenetics, developmental programming, cell fate specification, and transgenerational inheritance. Dedicated chapters explore experimental and computational tools, including bisulphite-based methods, ChIP-sequencing, microarrays, and bioinformatics resources essential for modern epigenomics research.

Designed as both a foundational reference and a practical research guide, this volume is indispensable for scientists working in genetics, molecular biology, biomedical research, and related disciplines. It also serves as a valuable resource for researchers entering the field who require a rigorous, up-to-date synthesis of epigenetic theory, methods, and applications.

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