Yersinia: Systems Biology and Control — ISBN 9781908230058

Description

The genus Yersinia includes some of the most consequential bacterial pathogens known to humans, ranging from Yersinia pestis—the causative agent of plague—to the enteropathogenic species Y. enterocolitica and Y. pseudotuberculosis, which are major but often under-recognized causes of gastroenteritis. Together, these organisms represent a complex public-health challenge shaped by re-emerging disease, antibiotic resistance, and evolving host–pathogen interactions.

Yersinia: Systems Biology and Control brings a systems-level perspective to the study of these pathogens, integrating genomic, transcriptomic, and proteomic approaches with applied concerns of surveillance, treatment, and prevention. Expert contributors review how Yersinia responds to host environments at the molecular level, how hosts mount immune responses, and how these dynamic interactions shape disease outcomes.

The volume covers contemporary topics including global gene-expression profiling during infection, comparative proteomics of bacterial and host responses, mechanisms of antibiotic resistance, vaccine development, epidemiological surveillance, and control strategies. Particular attention is given to Y. pestis as a re-emerging pathogen with biodefense implications, alongside enteropathogenic Yersinia species that represent a significant burden of gastrointestinal disease worldwide.

Designed for researchers rather than introductory readers, this book is essential reading for scientists working on Yersiniaand related organisms, and a valuable reference for those interested in microbial genomics, systems biology, infectious disease control, and the evolution of bacterial virulence.